Beta-Blocker Use in Pregnancy and Risk of Specific Congenital Anomalies: A European Case-Malformed Control Study

Beta-Blocker Use in Pregnancy and Risk of Specific Congenital Anomalies: A European Case-Malformed Control Study

INTRODUCTION The prevalence of chronic hypertension is increasing in pregnant women. Beta-blockers are among the most prevalent anti-hypertensive agents used in early pregnancy. OBJECTIVE The objective of this study was to investigate whether first-trimester use of beta-blockers increases the risk of specific congenital anomalies in offspring. METHODS A population-based case-malformed contr...

Use of asthma medication during pregnancy and risk of specific congenital anomalies: A European case-malformed control study.

BACKGROUND Pregnant women with asthma need to take medication during pregnancy. OBJECTIVE We sought to identify whether there is an increased risk of specific congenital anomalies after exposure to antiasthma medication in the first trimester of pregnancy. METHODS We performed a population-based case-malformed control study testing signals identified in a literature review. Odds ratios (ORs...

Beta-blocker use and risk of symptomatic bradyarrhythmias: a hospital-based case-control study

OBJECTIVE To investigate the risk factors of symptomatic bradyarrhythmias in relation to β-blockers use. METHODS A hospital-based case-control study [228 patients: 108 with symptomatic bradyarrhythmias (cases) and 120 controls] was conducted in Sultanah Aminah Hospital, Malaysia between January 2011 and January 2014. RESULTS The mean age was 61.1 ± 13.3 years with a majority of men (68.9%)....

Main Risk Factors for Ectopic Pregnancy: A Case-Control Study in A Sample of Iranian Women

prevalence of atopic dermatitis in children with type 1 diabetes mellitus in southeastern of iran (kerman province): a case-control study

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